Document Type
Article
Publication Date
2021
Abstract
Papillary Thyroid Cancer (PTC) accounts for 80–90% of all thyroid malignancies [1]. The most common morphology is the classical papillary which has an indolent course. Aggressive variants exist, of which Tall Cell Variant (TCV) is the most common. TCV is defined as a PTC in which 30% or more of tumor cells are 2-3 times as long as they are wide [1,2]. The histology image (Figure 1A, magnification 4x) shows tumor cells arranged back to back with abundant eosinophilic cytoplasm, and typical nuclear features of PTC; namely overlapping enlarged nuclei, intranuclear grooves, and occasional pseudoinclusions. Figure 1B (magnification: 20x) shows a high power view of the same case where the tall cell features of individual tumor cells can be better appreciated (arrows).
Recommended Citation
Shweta Agarwal. Tall Cell Variant of Papillary Thyroid Carcinoma: Recognizing a Rare Aggressive Variant. Annals Thyroid Res. 2021; 7(1): 320‐320. http://doi.org/10.26420/annalsthyroidres.2021.1077
