Going Back to Nature for Finding New Antibiotic to Fight Against the Mutated Bacteria (The Superbug)
Program
Chemistry and Chemical Biology
College
Arts and Sciences
Student Level
Doctoral
Start Date
10-11-2022 4:30 PM
End Date
10-11-2022 5:30 PM
Abstract
Living a healthy life is a well-desired thing for all human beings. But sometimes our health is affected by the pathogen specially by the bacteria and we get sick. In the event of sickness, we need medicine that can fight against pathogens and make our life back on the track that we always desire. Medicine, to be specific antibiotics has a great role in the treatment of diseases that are caused by bacteria. Right now, antibiotics are getting registrant due to the bacteria's own ability to mutate by itself. The antibiotic that is effective against the specific bacteria may not be effective in the near future for the same but mutated bacteria. So, we need to find out new antibiotics to treat the infection caused by the mutated bacteria. Finding a new and effective antibiotic is not easy because it requires a long process to find and screen a lot of lead compounds to get the desired antibiotic. For this purpose, we need to look through the natural compounds. In my research, I am trying to develop a way to make bacteria produce millions of different natural compounds and screen them all at the same time for getting potential antibiotics. This approach is very efficient compared to chemical synthesis to get a lot of new molecules within a short period of time because bacteria grow exponentially and produce peptides during their growth period.
Going Back to Nature for Finding New Antibiotic to Fight Against the Mutated Bacteria (The Superbug)
Living a healthy life is a well-desired thing for all human beings. But sometimes our health is affected by the pathogen specially by the bacteria and we get sick. In the event of sickness, we need medicine that can fight against pathogens and make our life back on the track that we always desire. Medicine, to be specific antibiotics has a great role in the treatment of diseases that are caused by bacteria. Right now, antibiotics are getting registrant due to the bacteria's own ability to mutate by itself. The antibiotic that is effective against the specific bacteria may not be effective in the near future for the same but mutated bacteria. So, we need to find out new antibiotics to treat the infection caused by the mutated bacteria. Finding a new and effective antibiotic is not easy because it requires a long process to find and screen a lot of lead compounds to get the desired antibiotic. For this purpose, we need to look through the natural compounds. In my research, I am trying to develop a way to make bacteria produce millions of different natural compounds and screen them all at the same time for getting potential antibiotics. This approach is very efficient compared to chemical synthesis to get a lot of new molecules within a short period of time because bacteria grow exponentially and produce peptides during their growth period.
