Do Bayley-III Composite Scores at 18-22 Months Corrected Age Predict Full-Scale IQ at 6-7 Years in Children Born Extremely Preterm?

Authors

Jean Lowe, Department of Pediatrics, University of New Mexico Health Sciences Center, Albuquerque, NM
Carla M. Bann, Social, Statistical and Environmental Sciences Unit, RTI International, Research Triangle Park, NC
Allison G. Dempsey, Department of Psychiatry, University of Colorado School of Medicine, University of Colorado Hospital, Denver, CO
Janell Fuller, Department of Pediatrics, University of New Mexico Health Sciences Center, Albuquerque, NM
H Gerry Taylor, Department of Pediatrics, Rainbow Babies & Children's Hospital, Case Western Reserve University, Cleveland, OH
Kathryn E. Gustafson, Department of Pediatrics, Abigail Wexner Research Institute at Nationwide Children's Hospital, The Ohio State University, Columbus, OH
Victoria E. Watson, Department of Pediatrics, Duke University, Durham, NC
Betty R. Vohr, Department of Pediatrics, Duke University, Durham, NC
Abhik Das, Department of Pediatrics, Women & Infants Hospital, Brown University, Providence, RI
Seetha Shankaran, Social, Statistical and Environmental Sciences Unit, RTI International, Rockville, MD
Kimberly Yolton, Department of Pediatrics, Wayne State University, Detroit, MI
M Bethany Ball, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH
Susan R. Hintz, Division of Neonatal and Developmental Medicine, Department of Pediatrics, Stanford University School of Medicine and Lucile Packard Children's Hospital, Palo Alto, CA
Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network

Document Type

Article

Publication Date

8-26-2023

Abstract

OBJECTIVE: To determine the ability of the Bayley-III cognitive and language composite scores at 18-22 months corrected age to predict WISC-IV Full Scale IQ (FSIQ) at 6-7 years in infants born extremely preterm.

STUDY DESIGN: Children in this study were part of the Neuroimaging and Neurodevelopmental Outcome cohort, a secondary study to the SUPPORT trial and born 24

RESULTS: Bayley-III cognitive (r = 0.33) and language scores (r = 0.44) were mildly correlated with WISC-IV FSIQ score. Of the children with Bayley-III cognitive scores of100, approximately 1 in 5 had an FSIQ of

CONCLUSIONS: Findings indicate the Bayley-III cognitive and language scores correlate with later IQ, but may fail to predict delay or misclassify children who are not delayed at school age. The Bayley-III can be a useful tool to help identify children born extremely preterm who have below average cognitive scores and may be at the greatest risk for ongoing cognitive difficulties.

TRIAL REGISTRATION: Extended Follow-up at School Age for the SUPPORT Neuroimaging and Neurodevelopmental Outcomes (NEURO) Cohort: NCT00233324.

Publisher

Mosby

Publication Title

The Journal of pediatrics

ISSN

1097-6833

Volume

263

First Page

113700

Last Page

113700

DOI

10.1016/j.jpeds.2023.113700

Language (ISO)

English

Recommended Citation

Lowe J, Bann CM, Dempsey AG, Fuller J, Taylor HG, Gustafson KE, Watson VE, Vohr BR, Das A, Shankaran S, Yolton K, Ball MB, Hintz SR; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Do Bayley-III Composite Scores at 18-22 Months Corrected Age Predict Full-Scale IQ at 6-7 Years in Children Born Extremely Preterm? J Pediatr. 2023 Aug 26;263:113700. doi: 10.1016/j.jpeds.2023.113700. Epub ahead of print. PMID: 37640232.