Document Type

Article

Publication Date

11-25-2021

Abstract

Background: Immune responses to vaccination are a known trigger for a new onset of glomerular disease or disease flare in susceptible individuals. Mass immunization against SARS-CoV-2 in the COVID-19 pandemic provides a unique opportunity to study vaccination-associated autoimmune kidney diseases. In the recent literature, there are several patient reports demonstrating a temporal association of SARS-CoV-2 immunization and kidney diseases.

Methods: Here, we present a series of 29 cases of biopsy-proven glomerular disease in patients recently vaccinated against SARS-CoV-2 and identified patients who developed a new onset of IgA nephropathy, minimal change disease, membranous nephropathy, ANCA-associated GN, collapsing glomerulopathy, or diffuse lupus nephritis diagnosed on kidney biopsies postimmunization, as well as recurrent ANCA-associated GN. This included 28 cases of

Results: The patients with collapsing glomerulopathy were of Black descent and had two

Conclusions: Glomerular disease to vaccination is rare, although it should be monitored as a potential adverse event.

Publication Title

Kidney360

ISSN

2641-7650

Volume

2

Issue

11

First Page

1770

Last Page

1780

DOI

10.34067/KID.0005372021

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