Current advances in transfusion medicine 2021: A critical review of selected topics by the AABB Clinical Transfusion Medicine Committee

Authors

Ryan A. Metcalf, Department of Pathology, University of Utah, Salt Lake City, Utah, USA
Claudia S. Cohn, Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota, USA
Elizabeth S. Allen, Department of Pathology, University of California San Diego, La Jolla, California, USA
Sara Bakhtary, Department of Laboratory Medicine, University of California San Francisco, San Francisco, California, USA
Thomas Gniadek, Department of Pathology, NorthShore University Health System, Chicago, Illinois, USA.
Gaurav Gupta, Department of Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Sarah Harm, Department of Pathology and Laboratory Medicine, University of Vermont, Burlington, Vermont, USA
Richard Haspel, Department of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
Aaron Hess, Department of Anesthesiology, University of Wisconsin, Madison, Wisconsin, USA
Jessica Jacobson, Department of Pathology, NYU Grossman School of Medicine, New York, New York, USA.
Parvez M. Lokhandwala, American Red Cross, Baltimore, Maryland, USA
Colin Murphy, Department of Pathology, University of Maryland, Baltimore, Maryland, USA
Jacqueline Poston, Department of Medicine, University of Vermont, Burlington, Vermont, USA
Micah T. Prochaska, Department of Medicine, University of Chicago, Chicago, Illinois, USA
Jay S. Raval, Department of Pathology, University of New Mexico, Albuquerque, New Mexico, USA
Nabiha H. Saifee, Seattle Children's Hospital, Seattle, Washington, USA
Eric Salazar, Department of Pathology, UT Health San Antonio, San Antonio, Texas, USA
Hua Shan, Department of Pathology, Stanford University, Palo Alto, California, USA
Nichole Zantek, Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota, USA
Monica B. Pagano, Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington, USA

Document Type

Article

Publication Date

7-1-2022

Abstract

BACKGROUND: Each year the AABB Clinical Transfusion Medicine Committee (CTMC) procures a synopsis highlighting new, important, and clinically relevant studies in the field of transfusion medicine (TM). This has been made available as a publication in Transfusion since 2018.

METHODS: CTMC members reviewed and identified original manuscripts covering TM-related topics published electronically (ahead-of-print) or in print from December 2020 to December 2021. Selection of publications was discussed at committee meetings and chosen based on perceived relevance and originality. Next, committee members worked in pairs to create a synopsis of each topic, which was then reviewed by additional committee members. The first and senior authors assembled the final manuscript. Although this synopsis is extensive, it is not exhaustive, and some articles may have been excluded or missed.

RESULTS: The following topics are included: blood products; convalescent plasma; donor collections and testing; hemoglobinopathies; immunohematology and genomics; hemostasis; patient blood management; pediatrics; therapeutic apheresis; and cell therapy.

CONCLUSIONS: This synopsis highlights and summarizes recent key developments in TM and may be useful for educational purposes.

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