Chemistry and Chemical Biology ETDs

Publication Date

10-18-1967

Abstract

A special interest in a nitramine rearrangement prompted the preparation of 1,4-diaminopyridazino [4,5-d] pyridazine and the nitration of this compound. Several reactions of the intermediates, which were synthesized en route to 1,4-diaminopyridazino [4,5-d] pyridazine, were studied. Strong evidence for the existence of keto-enol tautomerism was found in the case of 1,4-dihydroxypyridazino [4,5-d] pyridazine and its derivatives.

Some reactions of 5, 8-dichloropyrazino [2,3-d] pyridazine were studied with particular interest in the nucleophilic displacement of azides and in the nitration of 5,8-dianilinopyrazino [2,3-d] pyridazine.

The nitration of diaminophthalazine was also attempted in order to perform an acid catalyzed nitramine rearrangement from one ring to another. An experimental exploration into the substituted pyridazino [4,5-d] - (A), pyrazino [2,3-d] - (B) pyridazines and phthalazine (C), has been undertaken and discussed in this paper.

Project Sponsors

Sandia Corporation

Language

English

Document Type

Thesis

Degree Name

Chemistry

Level of Degree

Masters

Department Name

Department of Chemistry and Chemical Biology

First Committee Member (Chair)

Raymond N. Castle

Second Committee Member

Guido Herman Daub

Third Committee Member

Milton Kahn

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