Respiration, Succinoxidase and d-Amino Acid Oxidase Studies on Livers from Rats Fed the Hepatic Carcinogens 4-Dimethylaminoazobenzene (DAB) and 3(1)-Methyl-4-Dimethylaminoazobenzene(3(1)-Me-DAB)

Author

Donald R. Richmond

Publication Date

5-31-1955

Abstract

In 1933, Japanese workers produced liver cancer in rats by feeding o-amino-azo-toluene (cited by Rusch, et al. 1945, p.267). The carcinogenecity of the azo dyes became especially important since the incidence of these liver tumors varied profoundly with the composition of the diet in which it was given. Similar variations due to the diet had not been orbserved with the types of carcinogens. From further studies, in which known compenents were added to purified diets, both protective (anticarcinogenic) and augmenting (procarcinogenic) influences could be ascribed to individual components.

Language

English

Document Type

Dissertation

Degree Name

Biology

Level of Degree

Doctoral

Department Name

UNM Biology Department

First Committee Member (Chair)

Wilburn John Eversole

Second Committee Member

Martin William Fleck

Third Committee Member

William Jacob Koster

Recommended Citation

Richmond, Donald R.. "Respiration, Succinoxidase and d-Amino Acid Oxidase Studies on Livers from Rats Fed the Hepatic Carcinogens 4-Dimethylaminoazobenzene (DAB) and 3(1)-Methyl-4-Dimethylaminoazobenzene(3(1)-Me-DAB)." (1955). https://digitalrepository.unm.edu/biol_etds/289