Gloria D. Coronado, Kaiser Permanente Center for Health Research, 3800 N. Interstate Avenue, Portland, 97227, OR, United States
Renée M. Ferrari, University of North Carolina, Chapel Hill, Lineberger Comprehensive Cancer Center, Carolina Cancer Screening Initiative, Chapel Hill, 27514, NC, United States
Autumn Barnes, Research Triangle International, 3040 East Cornwallis Road, P.O. Box 12194, Research Triangle Park, 27709-2194, NC, United States
Sheila F. Castañeda, Department of Psychology, South Bay Latino Research Center, San Diego State University, 780 Bay Blvd Suite 200 ⎜ Chula Vista, 91910, CA, United States
Mark Cromo, Department of Internal Medicine, Healthy Kentucky Research Building, University of Kentucky, 760 Press Avenue, Room 343, Lexington, 40536-0679, KY, United States
Melinda M. Davis, Oregon Rural Practice-based Research Network, Department of Family Medicine & School of Public Health, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Mail Code L222, Portland, 97239, OR, United States
Mark Doescher, University of Oklahoma, Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Robert M. Bird Library, 1105 N. Stonewall Ave. LIB 175, Oklahoma City, 73117, OK, United States
Kevin English, Albuquerque Area Southwest Tribal Epidemiology Center, Albuquerque Area Indian Health Board, Inc., 7001 Prospect Place NE, Albuquerque, 87110, NM, United States
Jenna Hatcher, University of Arizona, University of Arizona Cancer Center, 1515 N. Campbell Avenue, Tucson, 85724, AZ, United States
Karen E. Kim, University of Chicago, University of Chicago, 5841 S. Maryland, MC 4076, Chicago, 60637, Il, United States
Sarah Kobrin, National Cancer Institute, Division of Cancer Control and Population Sciences, National Cancer Institute, 9609 Medical Center Drive, MSC 9762, Rockville, 20850, MD, United States
David Liebovitz, Feinberg School of Medicine, Northwestern University, 420 E. Superior St., Chicago, 60611, IL, United States
Shiraz I. Mishra, University of New Mexico Comprehensive Cancer Center and Departments of Pediatrics and Family and Community Medicine, University of New Mexico Health Sciences Center, Albuquerque, 87131, NM, United States
Jesse N. Nodora, Moores UC San Diego Cancer Center, University of California, 3855 Health Sciences Dr. #0901, San Diego, La Jolla, CA 92093, United States
Wynne E. Norton, National Cancer Institute, Division of Cancer Control and Population Sciences, National Cancer Institute, 9609 Medical Center Drive, MSC 9762, Rockville, 20850, MD, United States
Jill M. Oliveri, Ohio State University, College of Medicine and Comprehensive Cancer Center, 1590 North High Street, Suite 525, Columbus, 43201, OH, United States
Daniel S. Reuland, University of North Carolina, Chapel Hill, Lineberger Comprehensive Cancer Center, Carolina Cancer Screening Initiative, Chapel Hill, 27514, NC, United States
Sujha Subramanian, Research Triangle International, 3040 East Cornwallis Road, P.O. Box 12194, Research Triangle Park, 27709-2194, NC, United States
Jamie H. Thompson, Kaiser Permanente Center for Health Research, 3800 N. Interstate Avenue, Portland, 97227, OR, United States
Electra D. Paskett, Ohio State University, College of Medicine and Comprehensive Cancer Center, 1590 North High Street, Suite 525, Columbus, 43201, OH, United States

Document Type

Article

Publication Date

2-22-2023

Abstract

BACKGROUND: Although patient navigation has shown promise for increasing participation in colorectal cancer (CRC) screening and follow-up, little evidence is available to guide implementation of patient navigation in clinical practice. We characterize eight patient navigation programs being implemented as part of multi-component interventions of the National Cancer Institute's Cancer MoonshotSM Accelerating Colorectal Cancer Screening and Follow-Up Through Implementation Science (ACCSIS) initiative.

METHODS: We developed a data collection template organized by ACCSIS framework domains. The template was populated by a representative from each of the eight ACCSIS research projects. We report standardized descriptions of 1) the socio-ecological context in which the navigation program was being conducted; 2) navigation program characteristics; 3) activities undertaken to facilitate program implementation (eg, training); and 4) outcomes used in program evaluation.

RESULTS: ACCSIS patient navigation programs varied broadly in their socio-ecological context and settings, the populations they served, and in how they were implemented in practice. Six research projects adapted and implemented evidence-based patient navigation programs; the remaining projects developed new programs. Five projects began navigation when patients were due for initial CRC screening; three projects began navigation later in the screening process, when patients were due for follow-up colonoscopy after an abnormal stool-test result. Seven projects relied on existing clinical staff to deliver the navigation; one hired a centralized research navigator. All projects plan to evaluate effectiveness and implementation of their programs.

DISCUSSION: Our detailed program descriptions may facilitate cross-project comparisons and guide future implementation and evaluation of patient navigation programs in clinical practice.

CLINICALTRIALS.GOV REGISTRATION NUMBERS: Oregon: NCT04890054North Carolina: NCT044067San Diego: NCT04941300Appalachia: NCT04427527Chicago: NCT0451434Oklahoma: Not registeredArizona: Not registeredNew Mexico: Not registered.

Publisher

Oxford University Press

Publication Title

Journal of the National Cancer Institute

ISSN

1460-2105

DOI

10.1093/jnci/djad032

Language (ISO)

English

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