The Emergence of Zoonotic Onchocerca lupi Infection in the United States--A Case-Series.
Document Type
Article
Publication Date
3-15-2016
Abstract
This case-series describes the 6 human infections with Onchocerca lupi, a parasite known to infect cats and dogs, that have been identified in the United States since 2013. Unlike cases reported outside the country, the American patients have not had subconjunctival nodules but have manifested more invasive disease (eg, spinal, orbital, and subdermal nodules). Diagnosis remains challenging in the absence of a serologic test. Treatment should be guided by what is done for Onchocerca volvulus as there are no data for O. lupi. Available evidence suggests that there may be transmission in southwestern United States, but the risk of transmission to humans is not known. Research is needed to better define the burden of disease in the United States and develop appropriately-targeted prevention strategies.
Publisher
The University of Chicago Press
Publication Title
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
ISSN
1537-6591
Volume
62
Issue
6
First Page
778
Last Page
783
Recommended Citation
Cantey, Paul T; Jessica Weeks; Morven Edwards; Suchitra Rao; G Amin Ostovar; Walter Dehority; Maria Alzona; Sara Swoboda; Brooke Christiaens; Wassim Ballan; John Hartley; Andrew Terranella; Jill Weatherhead; James J Dunn; Douglas P Marx; M John Hicks; Ronald A Rauch; Christiana Smith; Megan K Dishop; Michael H Handler; Roy W R Dudley; Kote Chundu; Dan Hobohm; Iman Feiz-Erfan; Joseph Hakes; Ryan S Berry; Shelly Stepensaski; Benjamin Greenfield; Laura Shroeder; Henry Bishop; Marcos de Almeida; Blaine Mathison; and Mark Eberhard.
"The Emergence of Zoonotic Onchocerca lupi Infection in the United States--A Case-Series.."
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
