Corrigendum to "Unraveling the mechanobiology of immune cells" [Curr Opin Biotechnol 66 (2020) 236-245]

Authors

• Xuexiang Zhang, Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA 90095, USA
• Tae-Hyung Kim, Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Pathology, University of New Mexico School of Medicine
• Timothy J. Thauland, Division of Immunology, Allergy, and Rheumatology, Department of Pediatrics, University of California, Los Angeles, Los Angeles, CA 90095, USA
• Hongjun Li, Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA 90095, USA
• Fatemeh Sadat Majedi, Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA 90095, USA
• Chau Ly, Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA 90095, USA
• Zhen Gu, Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA 90095, USA
• Manish J. Butte, Division of Immunology, Allergy, and Rheumatology, Department of Pediatrics, University of California, Los Angeles, Los Angeles, CA 90095, USA
• Amy C. Rowat, Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA 90095, USA
• Song Li, Department of Bioengineering, University of California, Los Angeles, Los Angeles, CA 90095, USA

Document Type

Article

Publication Date

2-1-2022

Abstract

Immune cells can sense and respond to biophysical cues — from dynamic forces to spatial features — during their development, activation, differentiation and expansion. These biophysical signals regulate a variety of immune cell functions such as leukocyte extravasation, macrophage polarization, T cell selection and T cell activation. Recent studies have advanced our understanding on immune responses to biophysical cues and the underlying mechanisms of mechanotransduction, which provides rational basis for the design and development of immune-modulatory therapeutics. This review discusses the recent progress in mechanosensing and mechanotransduction of immune cells, particularly monocytes/macrophages and T lymphocytes, and features new biomaterial designs and biomedical devices that translate these findings into biomedical applications.

Comments

The authors regret that a few references were incorrectly cited in Table 1 . Reference [51] under “ECM Stiffness” should be replaced with [49]. [49] should be replaced with [50]. [50] should be replaced with [51]. [23] should be replaced with [20]. [51] under “Microstructure Confinement” should be replaced with [52]. The authors would like to apologise for any inconvenience caused.

Recommended Citation

Zhang X, Kim TH, Thauland TJ, Li H, Majedi FS, Ly C, Gu Z, Butte MJ, Rowat AC, Li S. Corrigendum to "Unraveling the mechanobiology of immune cells" [Curr Opin Biotechnol 66 (2020) 236-245]. Curr Opin Biotechnol. 2022 Feb;73:387-388. doi: 10.1016/j.copbio.2021.10.019. Epub 2021 Dec 9. Erratum for: Curr Opin Biotechnol. 2020 Dec;66:236-245. PMID: 34895976; PMCID: PMC8655620.