Clinical Performance of the Novel GenMark Dx ePlex Blood Culture ID Gram-Positive Panel

Authors

Karen C. Carroll
Jennifer L. Reid, Division of Medical Microbiology, Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA kcarrol7@jhmi.edu
Adam Thornberg, GenMark Diagnostics Inc., Carlsbad, California, USA
Natalie N. Whitfield, GenMark Diagnostics Inc., Carlsbad, California, USA
Deirdre Trainor, GenMark Diagnostics Inc., Carlsbad, California, USA
Shawna Lewis, Division of Medical Microbiology, Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
Teresa Wakefield, Division of Medical Microbiology, Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
Thomas E. Davis, Indiana University School of Medicine, Indianapolis, Indiana, USA
Keisha G. Church, Medical University of South Carolina, Charleston, South Carolina, USA
Linoj Samuel, Henry Ford Health System, Detroit, Michigan, USA
Ray Mills, Tricore Reference Laboratories, Albuquerque, New Mexico, USA
Patricia Jim, Tricore Reference Laboratories, Albuquerque, New Mexico, USA
Stephen Young, Tricore Reference Laboratories, Albuquerque, New Mexico, USA
Frederick S. Nolte, Medical University of South Carolina, Charleston, South Carolina, USA

Document Type

Article

Publication Date

3-25-2020

Abstract

Rapid identification from positive blood cultures is standard of care (SOC) in many clinical microbiology laboratories. The GenMark Dx ePlex Blood Culture Identification Gram-Positive (BCID-GP) Panel is a multiplex nucleic acid amplification assay based on competitive DNA hybridization and electrochemical detection using eSensor technology. This multicenter study compared the investigational-use-only (IUO) BCID-GP Panel to other methods of identification of 20 Gram-positive bacteria, four antimicrobial resistance genes, and both Pan

Recommended Citation

Carroll KC, Reid JL, Thornberg A, Whitfield NN, Trainor D, Lewis S, Wakefield T, Davis TE, Church KG, Samuel L, Mills R, Jim P, Young S, Nolte FS. Clinical Performance of the Novel GenMark Dx ePlex Blood Culture ID Gram-Positive Panel. J Clin Microbiol. 2020 Mar 25;58(4):e01730-19. doi: 10.1128/JCM.01730-19. PMID: 31996444; PMCID: PMC7098771.