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Contactin-1 (CNTN1), a cell adhesion and cell surface molecule, has been shown to be important for brain development. CNTN1 is suggested to be required for neuronal development and formation of myelin that protects the neurons. When CNTN1 is absent during development, it is lethal for the animal. The objective of this experiment is to elucidate the role of CNTN1 during brain development and myelination.

Funding: This research was supported by R01NS121660, UNM Comprehensive Cancer Center Support Grant NCI P30CA118100, and Taconic-Cyagen Custom Animal Model Awards.



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