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The goal of this project was to examine the effects of gut dysbiosis and gut-derived hydrogen sulfide on cognitive performance in humans. Hydrogen sulfide (H2S) is known to produce neurotoxic effects in relatively large amounts, yet it is produced by the body in tiny concentrations and has important roles. Here, we examined how moderate levels of H2S produced by gut bacteria may affect cognition.


This project was supported by the NIGMS Grant P20GM109089 and NINDS Grant R01NS129407



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