Effects of dysbiosis and gut-derived hydrogen sulfide on cognitive performance

Authors

• Kimberly Barnhart, The Mind Research Network, Lovelace Biomedical and Environmental Research Institute, Albuquerque, NM, USA
• Haley Prather, The Mind Research Network, Lovelace Biomedical and Environmental Research Institute, Albuquerque, NM, USA
• Stephanie Nitschke, The Mind Research Network, Lovelace Biomedical and Environmental Research Institute, Albuquerque, NM, USA
• Kayla Julio, The Mind Research Network, Lovelace Biomedical and Environmental Research Institute, Albuquerque, NM, USA
• Nicolas Shaff, The Mind Research Network, Lovelace Biomedical and Environmental Research Institute, Albuquerque, NM, USA
• Alexander Birg, Department of Gastroenterology, Raymond G. Murphy VA Medical Center, Albuquerque, NM, USA; Department of Internal Medicine; University of New Mexico School of Medicine, Albuquerque, NM, USA
• Henry Lin, Department of Gastroenterology, Raymond G. Murphy VA Medical Center, Albuquerque, NM, USA; Department of Internal Medicine; University of New Mexico School of Medicine, Albuquerque, NM, USA
• Sephira Ryman, The Mind Research Network, Lovelace Biomedical and Environmental Research Institute, Albuquerque, NM, USA; Nene and Jamie Kock Comprehensive Movement Disorder Center; Department of Neurology, University of New Mexico, Albuquerque, NM, USA
• Andrei Vakhtin, The Mind Research Network, Lovelace Biomedical and Environmental Research Institute, Albuquerque, NM, USA

Document Type

Poster

Publication Date

3-22-2024

Abstract

The goal of this project was to examine the effects of gut dysbiosis and gut-derived hydrogen sulfide on cognitive performance in humans. Hydrogen sulfide (H2S) is known to produce neurotoxic effects in relatively large amounts, yet it is produced by the body in tiny concentrations and has important roles. Here, we examined how moderate levels of H2S produced by gut bacteria may affect cognition.

FUNDING:

This project was supported by the NIGMS Grant P20GM109089 and NINDS Grant R01NS129407

Recommended Citation

Barnhart, Kimberly; Haley Prather; Stephanie Nitschke; Kayla Julio; Nicolas Shaff; Alexander Birg; Henry Lin; Sephira Ryman; and Andrei Vakhtin. "Effects of dysbiosis and gut-derived hydrogen sulfide on cognitive performance." (2024). https://digitalrepository.unm.edu/hsc-bbhrd/156