Third Trimester Equivalent Prenatal Alcohol Exposure Leads to Impaired Contextual Conditioning Paralleled by Blunted Activity of the Anteroventral Thalamus

Authors

Mitchell Morningstar, University of New Mexico School of Medicine and Health Sciences Center, Department of Neurosciences, Albuquerque, New Mexico, 87131, United States
David Linsenbardt, University of New Mexico School of Medicine and Health Sciences Center, Department of Neurosciences, Albuquerque, New Mexico, 87131, United States
Katalina Lopez, University of New Mexico School of Medicine and Health Sciences Center, Department of Neurosciences, Albuquerque, New Mexico, 87131, United States
Fernando Valenzuela, University of New Mexico School of Medicine and Health Sciences Center, Department of Neurosciences, Albuquerque, New Mexico, 87131, United States

Document Type

Poster

Publication Date

3-22-2024

Abstract

Fetal alcohol spectrum disorders result in a variety of learning and memory deficits. In this original study, we examined learning deficits between a third trimester equivalent alcohol exposure (TTAE) mouse model and their saline control counterparts. Additionally, we assessed the functional connectivity between 100+ brain regions using a marker of neural activity, cFOS. Overall, TTAE mice showed deficits in learning and differential network activation.

Recommended Citation

Morningstar, Mitchell; David Linsenbardt; Katalina Lopez; and Fernando Valenzuela. "Third Trimester Equivalent Prenatal Alcohol Exposure Leads to Impaired Contextual Conditioning Paralleled by Blunted Activity of the Anteroventral Thalamus." (2024). https://digitalrepository.unm.edu/hsc-bbhrd/147