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As cervical cancer becomes one of the most frequent cancer in women, the prevention methods as HPV vaccination and screening are being measured not only clinically but also economically. This paper is using dynamic optimal control model to find the optimal vaccination rate and screening rate to minimize the cost of vaccination, screening, and treatment for cervical cancer in developing countries. The simulation is under the south-Asian developing countries’ scenario. With the general form set up and different-scenario assumption discussion, the paper found the vaccination rate and screening rate are determined by the price and the dynamics of population change. By comparison to only having vaccination program or only screening program, having both vaccine and screening is cost-effective for cervical cancer prevention methods with the data based on the literature.

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Jan 1st, 12:00 AM

The Dynamic Optimal Control Model for Analyzing the Cost-effectiveness of Cervical Cancer Prevention in South-Asian Developing Countries

As cervical cancer becomes one of the most frequent cancer in women, the prevention methods as HPV vaccination and screening are being measured not only clinically but also economically. This paper is using dynamic optimal control model to find the optimal vaccination rate and screening rate to minimize the cost of vaccination, screening, and treatment for cervical cancer in developing countries. The simulation is under the south-Asian developing countries’ scenario. With the general form set up and different-scenario assumption discussion, the paper found the vaccination rate and screening rate are determined by the price and the dynamics of population change. By comparison to only having vaccination program or only screening program, having both vaccine and screening is cost-effective for cervical cancer prevention methods with the data based on the literature.