Health, Exercise, and Sports Sciences ETDs

Publication Date

Summer 7-29-2025

Abstract

Workers worldwide are at risk for acute kidney injury due to hyperthermia and dehydration as a consequence of exertional heat stress. Limited research has explored the impact which lifestyle agents such as beverages, recreational drugs, and medications have on core temperature, hydration, and risk of acute kidney injury during physical work in the heat. To address this research gap, we explored the impact of three agents frequently used by construction workers on thermoregulation and markers of risk of acute kidney injury. First, we investigated the effect which ibuprofen ingestion has prior to one hour of running in the heat on core temperature and markers of kidney injury. Then, we explored if caffeine contributed to exacerbated increases in core temperature and markers of kidney injury during two hours of walking in the heat. Lastly, we investigated the role of excessive previous night alcohol consumption on the same outcomes and measures during four hours of walking in the heat.

Keywords

AKI, Environmental Physiology, Renal, Alcohol, Caffeine, Ibuprofen

Document Type

Dissertation

Language

English

Degree Name

Physical Education, Sports and Exercise Science

Level of Degree

Doctoral

Department Name

Health, Exercise, and Sports Sciences

First Committee Member (Chair)

Fabiano Amorim

Second Committee Member

Flavio de Castro Magalhaes

Third Committee Member

Zachary Schlader

Fourth Committee Member

Zachary McKenna

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