Synthesis of 4, 7-disubstituted derivatives of imidazo-[4,5-d]-pyridazine and related compounds

Author

William Seese

Publication Date

7-3-1958

Abstract

When this study was contemplated, no imidazo [4,5-d] pyridazines had been reported in the literature. Compounds of special interest due to their possible antitumor activity were the 4,7-dimercapoto-, the 4,7-diamino-, the 4-mercapto-, and the 4-aminoimidazo [4,5-d] pyridazines together with unsubstituted imidazo [4,5-d] pyridazine. Key intermediates in the preparation of substituted amines in the ring system were the 4-chloro-, and the 4,7-dichloro- derivatives.

Language

English

Document Type

Thesis

Degree Name

Chemistry

Level of Degree

Masters

Department Name

Department of Chemistry and Chemical Biology

First Committee Member (Chair)

Raymond N. Castle

Second Committee Member

Jesse LeRoy Riebsomer

Third Committee Member

John Dustin Clark

Recommended Citation

Seese, William. "Synthesis of 4, 7-disubstituted derivatives of imidazo-[4,5-d]-pyridazine and related compounds." (1958). https://digitalrepository.unm.edu/chem_etds/80