Synthesis of 4, 7-disubstituted Derivatives of Imidazo-[4, 5-d]-pyridazine and Related Compounds

Author

William Seese

Publication Date

7-3-1958

Abstract

The antitumor activity of 8-azaguanine (5-amino-7-hydroxy-v-triasolo([d] pyrimidine) (A) prompted the preparation of the imidazo-[4, 5-d] pyridazine ring system (B). In this ring the two nitrogen atoms are adjacent in the six-membered ring with the five-membered imidazole ring remaining the same as in the parent purine ring (C).

Language

English

Document Type

Thesis

Degree Name

Chemistry

Level of Degree

Masters

Department Name

Department of Chemistry and Chemical Biology

First Committee Member (Chair)

Raymond N. Castle

Second Committee Member

Jesse LeRoy Riebsomer

Third Committee Member

John Dustin Clark

Recommended Citation

Seese, William. "Synthesis of 4, 7-disubstituted Derivatives of Imidazo-[4, 5-d]-pyridazine and Related Compounds." (1958). https://digitalrepository.unm.edu/chem_etds/80