Chemistry and Chemical Biology ETDs
Publication Date
12-27-1956
Abstract
Interest in carcinogenic compounds began to develop when a form of cancer was found occurring in chimney sweeps in 1775. Skin cancer was found among workers in tar industries in 1875, and in 1887 workers in cotton spinning industries were known to have cancer which was attributed to contact with lubricating oils. Girls who painted the luminous dials of watches contracted cancer from exposure to the radioactive paint, and men who worked with B-naphthylamine developed bladder cancer. Many other cases of occupational cancer were reported before a systematic study of carcinogenic substances was begun. Early attempts to produce cancer in rats and dogs by painting the skin with various chemicals failed, but in 1915 cancer was produced by application of coal tar to the ears of rabbits.
Project Sponsors
National Cancer Institute of the United States Public Health Service
Language
English
Document Type
Dissertation
Degree Name
Chemistry
Level of Degree
Doctoral
Department Name
Department of Chemistry and Chemical Biology
First Committee Member (Chair)
Guido Herman Daub
Second Committee Member
Jesse LeRoy Riebsomer
Third Committee Member
Raymond N. Castle
Fourth Committee Member
John Francis Suttle
Recommended Citation
Comp, Joseph Leonard Jr.. "The Synthesis of 7-Methyl-3,4-Benzpyrene, 6,7-Dimethyl-3,4-Benzpyrene, 10-Methyl-3,4-Benzpyrene and 7,10-Dimethyl-3,4-Benzpyrene." (1956). https://digitalrepository.unm.edu/chem_etds/110
