Biomedical Engineering ETDs
Publication Date
Summer 8-6-2020
Abstract
The cell surface is the first interface the host immune system encounters and
its investigation has led to a better understanding of cellular biology and types of
pathways that pathogens target in a host cell. The cell surface has evolved to include
many functions such as manipulation of the cytoskeleton, cell signaling, membrane
trafficking, adhesion, and integration into host tissue. The pathogens of interest are
the pathogenic fungus, Candida albicans, and the parasite, Giardia lamblia and we
investigate the consequences of drug treatments on the cell surface, leading to
promising new targets.
Language
English
Keywords
Candida albicans, Giardia lamblia, cell surface, dSTORM, drug discovery
Document Type
Dissertation
Degree Name
Biomedical Engineering
Level of Degree
Doctoral
Department Name
Biomedical Engineering
First Committee Member (Chair)
Aaron K. Neumann
Second Committee Member
Jeremy Edwards
Third Committee Member
David Keller
Fourth Committee Member
Siddhartha Das
Recommended Citation
Villalobos, Carmen M.. "The Investigation of Surface Structures on Various Pathogens and Their Interactions with the Human Immune System." (2020). https://digitalrepository.unm.edu/bme_etds/36
Included in
Immunology of Infectious Disease Commons, Other Biochemistry, Biophysics, and Structural Biology Commons, Other Biomedical Engineering and Bioengineering Commons, Pathogenic Microbiology Commons
