Biomedical Sciences ETDs

Publication Date

1-22-1970

Abstract

It is well known that passive antibody will specifically suppress an immune response to the corresponding antigen. The goal of this study was to determine if passive antibody had any effect on the development of immunological memory. The nature of the immune response to a second injection of sheep red blood cells (SRBC) following a primary immune response suppressed by passive antibody was investigated. C57Bl/Ks mice received a primary injection of SRBC and homologous anti-SRBC serum; 14 days later they were challenged with a second injection of SRBC. The immune response was evaluated by determining the number of cells synthesizing 19S or 7S anti-SRBC appearing in the spleens at intervals after immunization.

Document Type

Dissertation

Language

English

Degree Name

Biomedical Sciences

Level of Degree

Doctoral

Department Name

Biomedical Sciences Graduate Program

First Committee Member (Chair)

Sei Tokuda

Second Committee Member

Thomas N. [Unknown]

Third Committee Member

Frances N. [Unknown]

Fourth Committee Member

Robert E. [Unknown]

Fifth Committee Member

Joseph V. [Unknown]

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