Biology ETDs

Publication Date

Spring 5-1-2023

Abstract

Development of multicellular organisms depends on coordination of various molecular mechanisms to ensure proper tissue size and structure. This is accomplished through intrinsic and extrinsic cues that regulate cell growth and proliferation both spatially and temporally. These well-coordinated signals are present from early developmental stages and remain active throughout development to ensure tissue structure is appropriate for function. This is particularly important in early cell types that form specialized lineages such as stem cells or those found throughout the body such as epithelia. While much progress has been made in understanding growth regulatory mechanisms, several fundamental aspects remain unknown. This work elucidates new insights into some of the mechanisms that regulate tissue homeostasis in stem cells and epithelia using Drosophila as a model organism.

Project Sponsors

National Institutes of Health under award number R01 GM108756 , Winrock Doctoral Fellowship, and Excellence Fellowship

Language

English

Document Type

Dissertation

Degree Name

Biology

Level of Degree

Doctoral

Department Name

UNM Biology Department

First Committee Member (Chair)

Christopher Johnston

Second Committee Member

Helen Hathaway

Third Committee Member

Don Natvig

Fourth Committee Member

TyAnna Lovato

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Available for download on Thursday, May 15, 2025

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