Secondary to penetrating injuries, bacterial infections in the hand are well-reported and most frequently caused by gram-positive organisms. Although Staphylococcus and Streptococcus strains are the most common bacteria to infect the hand after an open injury, the musculoskeletal healthcare provider must be familiar with other potential infecting organisms when determining antibiotic coverage and management for the infected, traumatized hand. Prevotella denticola is a known colonizer of the gingiva and has been previously reported in oral and other systemic infections. Prevotella denticola may also present as a solitary pathogen or a participant in a mixed aerobic and anaerobic polymicrobial abscess. In this case report, the authors discuss a rare, deep hand infection in a previously healthy adult female with a Beta-lactamase positive Prevotella denticola and bacterial superinfection 8 months after a digital extensor tendon laceration and repair. Comprehensive culturing in hand infections should include anaerobic antibiotic susceptibility testing for secondary infections of the hand after penetrating trauma.


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