It is well established that alcohol exposure during prenatal development can lead to a heterogeneous and wide ranging set of morphological and neurobehavioral deficits that are collectively known as Fetal Alcohol Spectrum Disorders (FASDs). Previous neuroimaging research conducted on individuals with FASD has primarily employed graph-theoretical based analysis methods on functional imaging data to elucidate the impact of prenatal alcohol on brain connectivity. This study applied a widely used computational algorithm, group independent components analysis (gICA), to extract coherent sets of voxels that were correlated with one another as a measure of functional network connectivity (FNC) in a sample of adolescents and young adults with prenatal alcohol exposure. Connectivity measures were then compared to those of healthy controls and related to measures of intelligence. Increases in connectivity magnitude were observed in the Alcohol Related Neurodevelopmental Disorder (ARND) group.
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FASD, Prenatal Alcohol Exposure, Functional Connectivity
Rodriguez, Carlos I.. "The effects of prenatal alcohol exposure on the resting state functional brain connectivity in a sample of individuals with fetal alcohol spectrum disorder." (2018). https://digitalrepository.unm.edu/psy_etds/259