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Moderate prenatal alcohol exposure (mPAE; ~60-80 mg/dL) has been found to result in structural alterations to the hippocampus. Although many studies have shown that mPAE impairs performance on hippocampal-dependent tasks, few studies have compared behavior across male and female mPAE rats. Thus, the present study was aimed at comparing performance by male and female mPAE rats in tests of spatial memory and anxiety. Overall, mPAE didn't significantly affect spatial tasks but decreased anxiety-like behaviors.

This research was supported by R01 AA029700 and P50 AA022534.



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