It is an established fact that when warm-blooded animals are inoculated with foreign protein, in a great many instances they become immune, due to the formation of antibodies specific for the protein injected. In warm-blooded animals the body temperature is constant. The question naturally arises as to what the situation would be with regard to antibody formation in a cold-blooded animal where body temperature is not constant; also what part, if any, the temperature of the body would have to do with the antibody formation.
In a careful review of the literature practically nothing could be found in having direct bearing on the solution to this question. In order, then, to investigate this problem, a series of experiments was conduction on the cold-blooded animals kept at two different temperatures. The were inoculated with a foreign protein, a definite time was allowed for antibodies to form and their blood tested to determine the presence or absence of antibodies.
Antibodies, Homeothermic Mammals
Level of Degree
UNM Biology Department
First Committee Member (Chair)
Second Committee Member
Third Committee Member
McDaniel, Earl C.. "A Study of the Relation of Temperature to Antibody Formation in Cold-Blooded Animals." (1937). https://digitalrepository.unm.edu/biol_etds/194