Associations among diffusion tensor imaging and neurocognitive function in survivors of pediatric brain tumor: A pilot study.
The purpose of this study was to determine associations among neurocognitive outcomes and white matter integrity in the inferior fronto-occipital fasciculus (IFOF), uncinate fasciculus (UF), and genu of the corpus callosum (gCC) in survivors of pediatric brain tumor and healthy controls (HCs). Eleven survivors (ages 8-16; >2 years post-treatment) and 14 HCs underwent MRI; diffusion tensor imaging tractography (DSI Studio) was used to assess white matter integrity. Participants completed neuropsychological assessment of overall cognitive ability, executive function, processing speed, divided attention, and memory. As previously reported, survivors performed significantly worse than HCs on measures of overall IQ, working memory, processing speed, and executive function (
Appl Neuropsychol Child
Aleksonis, Holly A; Ryan Wier; Matthew M Pearson; Christopher J Cannistraci; Adam W Anderson; John F Kuttesch; Bruce E Compas; and Kristen R Hoskinson. "Associations among diffusion tensor imaging and neurocognitive function in survivors of pediatric brain tumor: A pilot study.." Appl Neuropsychol Child (2019): 1-12. doi:10.1080/21622965.2019.1613993.