Chemistry and Chemical Biology ETDs

Publication Date

8-31-1966

Abstract

There are many examples of nitro-substituted aromatic compounds, and of these the compounds in the benzene series have been most extensively studied. Nitro groups attached to an aromatic ring vary in reactivity toward nucleophilic displacement. For example, when two nitro groups are ortho or para to each other, one may be substituted with varying ease depending on the other substituents present. Nitro groups which are meta to one another are generally not subject to nucleophilic displacement. The mobility or ease of displacement of a nitro group by a nucleophile may be increased by introduction of other groups into the ring, and such effects are discussed by London and Robson, J. Chem. Soc., 242 (1937).

Language

English

Document Type

Dissertation

Degree Name

Chemistry

Level of Degree

Doctoral

Department Name

Department of Chemistry and Chemical Biology

First Committee Member (Chair)

Raymond N. Castle

Second Committee Member

Abraham Rosenzweig

Third Committee Member

Guido Herman Daub

Fourth Committee Member

Lee Duane Hansen

Fifth Committee Member

Roy Dudley Caton Jr.

Comments

National Institutes of Health, Sandia Corporation

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