Biology ETDs

Publication Date

5-20-1971

Abstract

The effects of Rickettsia typhi, Rickettsia rickettsii, and Coxiella burnetii infections on glucose metabolism in the chicken embryo were investigated. Cell-free extracts were prepared from infected and uninfected embryos and incubated with glucose-1-14C, glucose-6-14C, or gluconate- 6-14C. The results indicated that in typhus infected embryos a slight shift in glucose metabolism toward greater utilization of the hexose monophosphate pathway took place. Preliminary data obtained from Rocky Mountain spotted fever infected embryos suggested that infection with this organism has similar effect. Results obtained for Q fever infected embryos were not conclusive, but indicated that Q fever infection may result in slightly greater utilization of the glycolytic pathway. Possible mechanisms for these effects were discussed.

Language

English

Document Type

Dissertation

Degree Name

Biology

Level of Degree

Doctoral

Department Name

UNM Biology Department

First Committee Member (Chair)

John W. Beakley

Second Committee Member

Clarence Clayton Hoff

Third Committee Member

Gordon Verle Johnson

Fourth Committee Member

James Samuel Booth

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