Background and Purpose: Fatigue is the most commonly reported symptom among those with a diagnosis of Multiple Sclerosis (MS). There are approximately 2.5 million people with MS worldwide. The research presented looks at how exercise can affect fatigue in those with MS. It provides physical therapists evidence based findings regarding what interventions may positively change patients fatigue levels. Physical therapists play a key role in educating their patients how to positively affect fatigue and also have the ability to adapt exercise programs to suit the vastly different presentation and symptoms associated with MS. Case Description: This case study aims to answer the question illustrated by a female diagnosed with MS for the past 27 years. She hopes to find the energy to be able to participate in activities of daily living, play more with her grandchildren and decrease her dependence upon others with regards to dressing, bathing, transferring and mobility. This patient was only seen for a few days in an outpatient facility in Albuquerque, NM, therefore, there was not an implementation of intervention and all research was done post meeting this patient. Outcomes: There was no intervention plan implemented and no follow up with this patient. Patient history and two MS related fatigue scales, the Fatigue Severity Scale (FSS) and the Modified Fatigue Impact Scale (MFIS) were retrieved. Despite not getting my own data regarding outcomes specifically with this patient, I was able to assess many results regarding how exercise can affect fatigue in patients with MS. Through the article analysis on this topic I was able to determine the clinical exercise effect on fatigue for those with MS, however more research is indicated to determine specific exercise parameters. Discussion: The findings from this research analysis can be relatable to our own patients with similar backgrounds, characteristics, disease progression and symptom presentation. It is clear that future studies need to focus on exercise parameters, dosage, intensity and type and also classifying those with MS into more identifiable patient characteristic so interventions can match specific disease presentations. Future studies need to include differing types of MS as well as wider ranges of age. What has been found consistently is that exercise does not lead to disease progression or have deleterious effects on patient symptoms. It has been found to improve patient reported fatigue and improves activity levels in many studies. These findings are clinically'


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Faculty Advisor: Marybeth Barkocy, PT, DPT


Multiple Sclerosis, Fatigue, Physical Therapy, quality of life, Exercise