Biomedical Sciences ETDs

Publication Date

12-1-2015

Abstract

Most patients suffering from neuropathic pain will not obtain sufficient pain relief from current recommended therapy. The present study sought to compare patients with neuropathic pain treated with intrathecal drug delivery systems (IDDS) to those with oral opioid treatment alone via a retrospective analysis of electronic medical records. Pain scores and number and amount of adverse events were the primary endpoints of analysis. The most important finding of our study was that significantly fewer adverse events were found among patients treated with IDDS compared to patients treated with traditional oral medications. We examined the differences in recorded pain scores over time, but did not have statistically significant findings due to too many missing data points in the warehouse database. Future research will target pain outcomes utilizing a national database to enhance sample size.

Keywords

intrathecal drug delivery systems, neuropathic pain

Document Type

Thesis

Language

English

Degree Name

Biomedical Sciences

Level of Degree

Masters

Department Name

Biomedical Sciences Graduate Program

First Advisor

Milligan, Erin

First Committee Member (Chair)

Mishra, Shiraz

Second Committee Member

Koshkin, Eugene

Third Committee Member

N/A

Available for download on Thursday, December 14, 2017

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