Biomedical Sciences ETDs

Biomedical Sciences ETDs

 
The Biomedical Sciences Graduate Program is an integrated departmental program. It provides students with a broad-based, one-year core curriculum followed by focused course work and thesis/dissertation research. Research is conducted in faculty laboratories in the various basic science departments in the School of Medicine. In addition to our School of Medicine faculty, the BSGP is complemented by affiliated faculty in the UNM College of Pharmacy, Lovelace Respiratory Research Institute and Los Alamos National Laboratory who may direct graduate student research. To receive their degree, students fulfill the requirements of the BSGP in one of six Research Areas.

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Dissertations

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Role of cytochrome P4501A1 in vasoreactivity and blood pressure regulation mediated by omega-3 polyunsaturated fatty acids, Njotu Agbor

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Assessment of functional characteristics of small GTPases using small molecules, Jacob Agola

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Studies on spreading depolarization in healthy and metabolically compromised brain tissues, Isamu Aiba

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G-Protein Coupled Estrogen Receptor Regulation of Migration and Metastasis in the Breast, Sara Alcon

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The role of diffusion and membrane topography in the initiation of high affinity IgE receptor signaling, Nicholas Andrews

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Inhaled multiwalled carbon nanotubes induce systemic inflammation and endothelial dysfunction via MMP-9 induction, Mario Aragon

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Gene-environment interactions affect long-term depression (LTD) through changes in dopamine D2 receptor affinity in Snap25 haplodeficient mice, Michael Baca

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Adult neural stem/progenitor cells in response to their microenvironment : proliferation, differentiation, and migration, Basam Barkho

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Role of Rab7 in the pathogenesis of Charcot-Marie-Tooth Type2B (CMT2B) Disease, Soumik BasuRay

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The RNA binding protein KSRP destabilizes GAP-43 mRNA to limit axonal elongation in cultured hippocampal neurons, Clark Bird

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Prenatal Alcohol Exposure Effects on NMDA Receptor Subunit Composition and Function in the Mouse Dentate Gyrus, Megan Brady

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Regulation of cyclin E stability in Xenopus laevis embryos, Yekaterina Brandt (Webb)

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The RNA binding and RNA chaperone activity of Sin Nombre virus nucleocapsid, Bradley Brown

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Engineering Catalytic Molecular Logic Devices for Biodetection, Carl Brown III

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EFFECTS OF LOW-DOSE GAMMA RADIATION IN A MURINE MODEL OF BENZO[A]PYRENE-INDUCED LUNG CANCER, Veronica Bruce

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Induction of interleukin-10 within the T(H)17 effector population using the GPER agonist G-1, Ryan Brunsing

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Alterations in neuromodulators of GABAergic transmission in the cerebellar cortex of patients with schizophrenia., William Michael Bullock

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Role of hypoxia-inducible factor-1 alpha in neural stem/progenitor cell function following hypoxia, Kate M. Candelario

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Synaptic Zn2+ release during spreading depolarizations : implications for ischemic brain injury, Russell Carter

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Mechanisms of Innate Immune Regulation of Dermonecrosis during Staphylococcus aureus skin infections, Moriah Castleman

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Yeast V-ATPase Regulation by Phosphofructokinase-1, Chun-Yuan Chan

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Dynamics of cell-cell junctions in keratinocytes, Miquella Chavez

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Mechanisms of augmented coronary artery constriction following exposure to diesel exhaust, Tom Cherng

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Bacteriophage virus-like particles as vaccine platforms : from heart disease to malaria, Erin Crossey

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Elastomeric Capture Microparticles (ECµPs) and Their Use with Acoustophoresis to Perform Affinity Capture Assays, Kevin Cushing

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Membrane-Protein Dynamics: New Perspectives in FcepsilonRI Signaling through Single Particle Tracking, Patrick Cutler

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Inhibition of Virulence as Treatment Strategies for Staphylococcus aureus Infection, Seth Michael Daly

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Protein carbonylation, protein aggregation and cell death in a murine model of multiple sclerosis, Anushka Dasgupta

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The role of metnase in DNA replication fork stress response and DNA damage, Leyma De Haro

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Immune regulation of the host autophagic response and the elimination of Mycobacterium tuberculosis, Sergio A. De Haro

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Exploring the use of synthetic delivery platforms and small molecule adjuvants to improve the efficacy of spinal interleukin-10 gene therapy for chronic neuropathic pain, Ellen Dengler

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Identification and characterization of steroid receptor ligands, Megan Dennis

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Relative contributions of zinc and calcium to acute injury to hippocampal CA1 neurons, Robert Dietz

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Roles of autophagy in HIV-1 infection, Christina Dinkins

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MECHANISMS OF LOW DOSE ARSENIC LYMPHOID STEM CELL IMMUNOTOXICITY AND POTENTIAL INTERACTIONS WITH DIBENZO[def, p]CHRYSENE (DBC), Peace Chinyere Ezeh

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Novel mechanisms of androgen receptor degradation by alpha-tocopherylquinone and curcumin analog 27, Alexandra Fajardo

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Novel α-MSH Peptide Analogs for Melanoma Targeting, Adam Flook

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Crosstalk between adipocytes and immune cells in adipose tissue in an obese inflammatory state: role of contact-mediated signaling, Carolina Franco Nitta

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The Role of G protein-coupled estrogen receptor in vascular function and hypertension, Natalie C. Fredette

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Characterization of subspecies B1 human adenovirus ORF E3-10.9K, Kathryn Marie Frietze

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Evaluation of the Epidermal Growth Factor Receptor Signaling Pathway as a Therapeutic Target in Human Papillomavirus-Associated Disease, Anastacia Griego

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R-ketorolac targets Cdc42 and Rac1 and alters ovarian cancer behaviors critical for invasion and metastasis, Yuna Guo

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Assessment of field effect in the cancerous prostate, Christina Haaland

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Legacy mining metal exposures contribute to circulating oxidized low density lipoprotein and serum inflammatory potential in a native community, Molly Harmon

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Next-Generation Sequencing: Acquisition, Analysis, and Assembly, Antoine Ho

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An ongoing pulmonary cowpox virus infection suppresses an immune response to OVA peptide delivered to the lungs, Cara Hrusch

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Induction of mucosal immunity using virus-like particle based vaccines, Zoe Hunter

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Mechanisms of hydrogen sulfide induced vasodilation, Olan Jackson-Weaver

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The Role of OFD1 in the Pathogenesis of Polycystic Kidney Disease, Stephanie Jerman

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MOLECULAR MECHANISM OF AUTOPHAGY-BASED UNCONVENTIONAL SECRETION OF IL-β, Shanya Jiang

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Engineering RNA phage MS2 virus-like particles for peptide display, Sheldon Keith Jordan

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Functions of autophagy in lipid homeostasis and survival in androgen-dependent prostate cancer cells, Ramesh Kaini

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Biomolecular signatures of severe malarial anemia, Zachary Karim

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Characterization of R-ketorolac as a single enantiomer selective inhibitor of Cdc42 and Rac1 in ovarian cancer, Shelby Kenney

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Impact of Environmental Enrichment on Adult Hippocampal Neurogenesis in a Preclinical Mouse Model of Fetal Alcohol Spectrum Disorder (FASD), Kajimoto Kenta

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The Contribution of Poly(ADP-ribose)polymerase-1 Activity in the Nucleotide Excision Repair Pathway, Brenee S. King

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Genetic contributions to brain fiber architecture and neuroanatomical alterations in alcohol dependent individuals : a correlation study, Vibhati Kulkarny

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The Differential Contribution of Behavior and Biology to Breslow Thickness and Melanoma Survival in Males Compared to Females, Jenna Lilyquist

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DISPLAY OF PEPTIDES AND SINGLE-CHAIN ANTIBODIES ON BACTERIOPHAGE MS2 VIRUS-LIKE PARTICLES, Christopher Andrew Lino

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Live cell kinetics of erbB dimerization reveals influences of activation state and membrane organization, Shalini Low-Nam

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Apolipoprotein B containing lipoproteins contribute to host innate immune pulmonary defense against Staphylococcus aureus, Brett Manifold-Wheeler

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Antibody-mediated protection against pulmonary infection with virulent type A Francisella tularensis, Gopi Mara-Koosham

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Immune regulation and Fc(alpha)RI Recognition and activation by C-reactive protein, Kristopher Marjon

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In Vivo Characterization of G Protein-Coupled Estrogen Receptor in Mammary Tumorigenesis, Nicole Marjon

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Perinatal arsenic exposure inhibits binding ability of glucocorticoid receptors to nuclear response elements altering gene expression and affecting learning behavior, Ebany Martinez-Finley

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Mechanisms of Enhanced Pulmonary Vasoconstriction and Calcium Sensitization Following Chronic Hypoxia, Charles Elbert Norton III

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Population dynamics of flaviviruses in the United States, Kendra Pesko

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Apolipoprotein B-mediated control of Staphylococcus aureus virulence, Meghan Michal Peterson

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Neuropathogenesis of highly pathogenic avian influenza in ferrets following intranasal instillation or aerosol exposure to low doses, Jennifer Plourde

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Pulmonary BCG vaccination for uniform protection against tuberculosis in environmental mycobacteria endemic regions, Dominique N. Price

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Ethanol exposure impairs glutamatergic synaptic transmission and plasticity in the ca1 hippocampal region during the third trimester-equivalent of human pregnancy : implications for fetal alcohol spectrum disorder, Michael Puglia

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The Role of Snai2/Slug in Diabetes-impaired Wound Healing, Krystle K. Quan

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Changes in c-Myb activity during proliferation, Anita Quintana

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Cellular localization and expression of Ski family proteins in rhabdomyosarcoma, Brian Reinert

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Role of endothelial BKCa channel activity in diminished vasoconstrictor reactivity following chronic hypoxia, Melissa Riddle

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Microsphere based protease assays and high throughput screening of bacterial toxin proteases, Matthew Saunders

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Characterization of G protein-coupled estrogen receptor (GPER) in breast epithelial proliferation and morphogenesis, Allison Scaling

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Development of presynaptic calcium dynamics and short-term plasticity in the SC-Ca1 synapse, Chessa Scullin

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Regulation of spreading depression events in brain slices by astrocyte metabolism, Jessica L. Seidel

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Defining and Assessing Problem Solving Across a Biochemistry Curriculum, Cheryl A. Sensibaugh

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Carbonylation of neuronal cytoskeletal proteins and their proteolytic degradation in acute experimental autoimmune encephalomyelitis, Suzanne Smerjac

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Entry and trafficking of human papillomavirus type 31 into human keratinocytes, Jessica Smith

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Epigenetic regulation of neuronal maturation : the effect of MeCP2 and MicroRNAs on the maturation of hippocampal neurons, Richard Smrt

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Pulmonary vasoconstrictor reactivity following intermittent hypoxia, Jessica Snow

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Inducible heat shock protein 70 enhances human papillomavirus type 31 genome replication, viral capsid protein nuclear localization and progeny virion morphogenesis in human keratinocytes, Hebin Song

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Consequences of Prenatal Ethanol Exposure and Maternal Stress on Offspring, Miranda Staples

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Paratransgenic control of vibriosis in shrimp aquaculture, Bobban Subhadra

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Small molecule inhibition of Staphylococcus aureus virulence, Erin Sully

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SNAP-25 is a component of a ubiquitous SNARE complex required for evoked neuroexocytosis in GABAergic neurons, Lawrence C. R. Tafoya

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Multifunctional iron platinum stealth immunomicelles : targeted imaging and therapy of prostate cancer., Robert Taylor

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CD82 membrane scaffolding regulates hematopoietic cell functions, Christina M. Termini

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Exposure of neonatal rats to alcohol has differential effects on cytokine levels in the cerebellum and hippocampus : potential role of microglia and astrocytes, Lauren Topper

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Aberrant neurogenic and epigenetic processes are associated with depression induced by developmental arsenic exposure, Christina Rene Tyler

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Development of HPV next-generation virus-like particle vaccines that are cross-protective, Mitchell Tyler

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The role of Bcl-2 modifying factor (Bmf) in airway epithelial cell death, Amelia H.T. Unione

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Prenatal alcohol exposure alters histamine H3 receptor modulation of glutamate release and long-term potentiation in the rat dentate gyrus, Rafael Varaschin

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THE IMMUNOLOGICAL MECHANISMS OF INFLUENZA VACCINATION: A COMPARISON BETWEEN A SEASONAL SUBUNIT VACCINE AND AN H5N1 SUBUNIT VACCINE WITH AND WITHOUT ALUM ADJUVANT, Sarah Vaughan

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Regulation of N-formyl peptide receptor trafficking and signaling by arrestins, Brant Wagener

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Role of MMPs and TIMP-3 in neuronal death and white matter injury following transient global ischemia., Espen Walker

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GCN5L1 Functions as a Mitochondrial Acetyltransferase that Regulates Mitophagy, Bradley Roy Webster